Comprehensive Psychiatry
Volume 51, Issue 5 , Pages 471-479 , September 2010

Neurocognition in schizophrenia: a 20-year multi–follow-up of the course of processing speed and stored knowledge

References 

  1. Heinrichs RW, Zakzanis KK. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology. 1998;12:426–445
  2. Aleman A, Hijman R, de Haan EH, Kahn RS. Memory impairment in schizophrenia: a meta-analysis. Am J Psychiatry. 1999;166:1358–1366
  3. Lee J, Park S. Working memory impairments in schizophrenia: a meta-analysis. J Abnorm Psychology. 2005;114:599–611
  4. Velligan DI, Bow-Thomas CC. Executive function in schizophrenia.. Semin Clin Neuropsychiatry. 1999;4:24–33
  5. Saykin AJ, Shtasel DL, Gur RE, Kester DB, Mozley LH, Stafiniak P, et al. Neuropsychological deficits in neuroleptic naïve patients with first-episode schizophrenia. Arch Gen Psychiatry. 1994;51:124–131
  6. Kurtz MM. Neurocognitive impairment across the lifespan in schizophrenia: an update. Schizophr Res. 2005;74:15–26
  7. Gold S, Arndt S, Nopoulos P, O'Leary DS, Andreasen NC. Longitudinal study of cognitive function in first-episode and recent-onset schizophrenia. Am J Psychiatry. 1999;156:1342–1348
  8. Hoff AL, Sakuma M, Wieneke M, Horon R, Kushner M, DeLisi LE. Longitudinal neuropsychological follow-up study of patients with first-episode schizophrenia. Am J Psychiatry. 1999;156:1336–1341
  9. Russell AJ, Munro JC, Jones PB, Hemsley DR, Murray RM. Schizophrenia and the myth of intellectual decline. Am J Psychiatry. 1997;154:635–639
  10. David A. Schizophrenia and intellectual decline. Am J Psychiatry. 1998;155:1634–1635
  11. Kremen WS, Buka SL, Seidman LJ, Goldstein JM, Koren D, Tsuang MT. IQ decline during childhood and adult psychotic symptoms in a community sample: a 19-year longitudinal study. Am J Psychiatry. 1998;155:672–677
  12. Sheitman BB, Murray MG, Snyder JA, Silva S, Goldman R, Chakos M, et al. IQ scores of treatment-resistant schizophrenia patients before and after the onset of the illness. Schizophr Res. 2000;46:203–207
  13. Harvey PD, Silverman JM, Mohs RC, Parrella M, White L, Powchik P, et al. Cognitive decline in late-life schizophrenia: a longitudinal study of geriatric chronically hospitalized patients. Biol Psychiatry. 1999;45:32–40
  14. Amminger GP, Edwards J, Brewer WJ, Harrigan S, McGorry PD. Duration of untreated psychosis and cognitive deterioration in first-episode schizophrenia. Schizophr Res. 2002;54:223–230
  15. Lappin JM, Morgan KD, Morgan C, Dazzan P, Reichenberg A, Zanelli JW, et al. Duration of untreated psychosis and neuropsychological function in first episode psychosis. Schizophr Res. 2007;95:103–110
  16. Rund BR, Sundet K, Asbjornsen A, Egeland J, Landro NI, Lund A, et al. Neuropsychological test profiles in schizophrenia and non-psychotic depression. Acta Psychiatr Scand. 2006;113:350–359
  17. Dickinson D, Ragland JD, Gold JM, Gur RC. General and specific cognitive deficits in schizophrenia: Goliath defeats David?. Biol Psychiatry. 2008;64:823–827
  18. Dickinson D, Ramsey ME, Gold JM. Overlooking the obvious: a meta-analytic comparison of digit symbol coding tasks and other cognitive measures in schizophrenia. Arch Gen Psychiatry. 2007;64:532–542
  19. Burdick KE, Goldberg JF, Harrow M, Faull RN, Malhotra AK. Neurocognition as a stable endophenotype in bipolar disorder and schizophrenia. J Nerv Ment Dis. 2006;194:255–260
  20. Harrow M, Grossman LS, Jobe TH, Herbener ES. Do patients with schizophrenia ever show periods of recovery? A 15-year multi-follow-up study. Schizophr Bull. 2005;31:723–734
  21. Harrow M, Jobe TH, Herbener ES, Goldberg JF, Kaplan KJ. Thought disorder in schizophrenia: working memory and impaired context. J Nerv Ment Dis. 2004;192:3–11
  22. Harrow M, Jobe TH. How frequent is chronic multiyear delusional activity and recovery in schizophrenia: a 20-year multi-follow-up. Schizophr Bull doi:10.1093/schbul/sbn074.
  23. Reed RA, Harrow M, Herbener ES, Martin EM. Executive function in schizophrenia: is it linked to psychosis and poor life functioning?. J Nerv Ment Dis. 2002;190:725–732
  24. Strauss GP, Harrow M, Grossman LS, Rosen C. Periods of recovery in deficit syndrome schizophrenia: a 20-year multi-follow-up longitudinal study. Schizophr Bull doi:10.1093/schbul/sbn167.
  25. Spitzer RL, Endicott J, Robins E. Research diagnostic criteria: rationale and reliability. Arch Gen Psychiatry. 1978;35:773–782
  26. Endicott J, Spitzer RL. A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry. 1978;35:837–844
  27. Grinker R, Harrow M. Clinical research in schizophrenia: a multidimensional approach. Springfield (Ill): Charles C. Thomas; 1987;
  28. McGrath JJ. Myths and plain truths about schizophrenia epidemiology—the NAPE lecture 2004. Acta Psychiatr Scand. 2005;111:4–11
  29. Bleuler M. The Schizophrenic disorders: long-term patient and Family Studies. New Haven: Yale University Press; 1978;
  30. Harrison G, Hopper K, Craig T, Laska E, Siegel C, Wanderling J, et al. Recovery from psychotic illness: a 15- and 25-year international follow-up study. Br J Psychiatry. 2001;178:506–517
  31. Wechsler D. Manual for the Wechsler adult intelligence scale. New York: The Psychological Corp; 1955;
  32. Putnam KM, Harvey PD. Memory performance of geriatric and nongeriatric chronic schizophrenic patients: a cross-sectional study. J Int Neuropsychol Soc. 1999;5:494–501
  33. Zorilla LTE, Heaton RK, McAdams LA, Zisook S, Harris MJ, Jeste DV. Cross-sectional study of older outpatients with schizophrenia and healthy comparison subjects: no differences in age-related cognitive decline. Am J Psychiatry. 2000;157:1324–1326
  34. Reichenberg A, Harvey PD, Bowie CR, Mojtabai R, Rabinowitz J, Heaton RK, et al. Neuropsychological function and dysfunction in schizophrenia and psychotic affective disorders. Schizophr Bull doi:10.1093/schbul/sbn044.
  35. Bilder RM, Lipschutz-Broch L, Reiter G, Geisler SH, Mayerhoff DI, Lieberman JA. Intellectual deficits in first-episode schizophrenia: evidence for progressive deterioration. Schizophr Bull. 1992;18:437–448
  36. Weinberger DR. Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry. 1987;44:660–669
  37. Rund BR. A review of longitudinal studies of cognitive functions in schizophrenia patients. Schizophr Bull. 1998;24:425–435
  38. Woods BT. Is schizophrenia a progressive neurodevelopmental disorder? Toward a unitary pathogenic mechanism. Am J Psychiatry. 1998;155:1661–1670
  39. Zipparo L, Whitford TJ, Redoblado Hodge MA, Lucas S, Farrow TF, Brennan J, et al. Investigating the neuropsychological and neuroanatomical changes that occur over the first 2-3 years of illness in patients with first-episode schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32:531–538
  40. Hoff AL, Svetina C, Shields G, Stewart J, DeLisi LE. Ten year longitudinal study of neuropsychological functioning subsequent to a first episode of schizophrenia. Schizophr Res. 2005;28:27–34
  41. Albus M, Hubmann W, Scherer J, Dreikorn B, Hecht S, Sobizack N, et al. A prospective 2-year follow-up study of neurocognitive functioning in patients with first-episode schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2002;252:262–267
  42. Heaton RK, Gladsjo JA, Palmer BW, Kuck J, Marcotte TD, Jeste DV. Stability and course of neuropsychological deficits in schizophrenia. Arch Gen Psychiatry. 2001;58:24–32
  43. Hyde TM, Nawroz S, Goldberg TE, Bigelow LB, Strong D, Ostrem JL, et al. Is there cognitive decline in schizophrenia? A cross-sectional study. Br J Psychiatry. 1994;164:494–500
  44. Friedman JI, Harvey PD, Coleman T, Moriarty PJ, Bowie C, Parrella M, et al. Six-year follow-up study of cognitive and functional status across the lifespan in schizophrenia: a comparison with Alzheimer's disease and normal aging. Am J Psychiatry. 2001;158:1441–1448
  45. Dikmen S.S., Heaton R.K., Grant I., Temkin N.R. Test-retest reliability and practice effects of expanded Halstead-Reitan Neuropsychological Test Battery. J Int Neuropsychol Soc 5:346-56.
  46. McCaffrey RJ, Ortega A, Haase RF. Effects of repeated neuropsychological assessments. Arch Clin Neuropsychol 8:519-24.
  47. Bonner-Jackson A, Grossman LS, Harrow M, Rosen C. Neurocognitive predictors of future recovery in schizophrenia: A 20-year follow-up. Schizophr Bull. 2009;35:292
  48. Loebel AD, Lieberman JA, Alvir JM, Mayerhoff DI, Geisler SH, Szymanski SR. Duration of psychosis and outcome in first-episode schizophrenia. Am J Psychiatry. 1992;149:1183–1188
  49. McGlashan T. Is active psychosis neurotoxic?. Schizophr Bull. 2006;32:609–613

 Funding: the authors have no conflict of interest or financial relationships to disclose. This research was supported in part by USPH grants MH-26341 and MH-068688 by NIMH (Dr. Harrow).

PII: S0010-440X(10)00008-8

doi: 10.1016/j.comppsych.2010.02.005

Comprehensive Psychiatry
Volume 51, Issue 5 , Pages 471-479 , September 2010