Comprehensive Psychiatry
Volume 50, Issue 5 , Pages 415-423 , September 2009

Suicidality, aggression, and other treatment considerations among pregnant, substance-dependent women with posttraumatic stress disorder

  • A. Meade Eggleston

      Affiliations

    • VA Mid-Atlantic Mental Illness Research, Education and Clinical Center (MIRECC), Durham VA Medical Center, Durham, NC 27705, USA
    • Corresponding Author InformationCorresponding author.
    • ,
  • Patrick S. Calhoun

      Affiliations

    • VA Mid-Atlantic Mental Illness Research, Education and Clinical Center (MIRECC), Durham VA Medical Center, Durham, NC 27705, USA
    • Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA
    • ,
  • Dace S. Svikis

      Affiliations

    • Department of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA
    • ,
  • Michelle Tuten

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    • ,
  • Margaret S. Chisolm

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    • ,
  • Hendree E. Jones

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

References 

  1. Brady KT. Posttraumatic stress disorder and comorbidity: recognizing the many faces of PTSD. J Clin Psychiatry. 1997;58(Suppl 9):12–15
  2. Brown PJ, Wolfe J. Substance abuse and post-traumatic stress disorder comorbidity. Drug Alcohol Depend. 1994;35(1):51–59
  3. Dansky BS, Saladin ME, Brady KT, Kilpatrick DG, Resnick H. Prevalence of victimization and posttraumatic stress disorder among women with substance use disorders: comparison of telephone and in-person assessment samples. Int J Addict. 1995;30(9):1079–1099
  4. Kessler RC. The national comorbidity survey: preliminary results and future directions. Int J Methods Psychiatr Res. 1995;5(2):139–151
  5. American Psychiatric Association . Diagnostic and statistical manual of mental disorders. 4th ed.. Washington, D.C.: Author; 1994;
  6. Najavits LM, Weiss RD, Shaw SR. The link between substance abuse and posttraumatic stress disorder in women: a research review. Am J Addict. 1997;6(4):273–283
  7. Brady KT, Killeen T, Saladin ME, Dansky B, Becker S. Comorbid substance abuse and posttraumatic stress disorder: characteristics of women in treatment. Am J Addict. 1994;3(2):160–164
  8. Najavits LM, Weiss RD, Reif S, Gastfriend DR, Siqueland L, Barber JP, et al. The Addiction Severity Index as a screen for trauma and posttraumatic stress disorder. J Stud Alcohol. 1998;59(1):56–62
  9. Brown PJ, Stout RL, Mueller T. Posttraumatic stress disorder and substance abuse relapse among women: a pilot study. Psychol Addict Behav. 1996;10(2):124–128
  10. Mills KL, Teesson M, Ross J, Darke S. The impact of post-traumatic stress disorder on treatment outcomes for heroin dependence. Addiction. 2007;102(3):447–454
  11. Brady KT, Lydiard RB. The association of alcoholism and anxiety. Psychiatr Q. 1993;64(2):135–149
  12. Brooner R, King V, Kidorf M, Schmidt CJ, Bigelow G. Psychiatric and substance use comorbidity among treatment-seeking opioid abusers. Arch Gen Psychiatry. 1997;54:71–80
  13. Grilo CM, Martino S, Walker ML, Becker DF, Edell WS, McGlashan TH. Controlled study of psychiatric comorbidity in psychiatrically hospitalized young adults with substance use disorders. Am J Psychiatry. 1997;154(9):1305–1307
  14. Kidorf M, Disney ER, King VL, Neufeld K, Beilenson PL, Brooner RK. Prevalence of psychiatric and substance use disorders in opioid abusers in a community syringe exchange program. Drug Alcohol Depend. 2004;74(2):115–122
  15. Compton WM, Cottler LB, Jacobs JL, Ben-Abdallah A, Spitznagel EL. The role of psychiatric disorders in predicting drug dependence treatment outcomes. Am J Psychiatry. 2003;160(5):890–895
  16. Greenfield SF, Brooks AJ, Gordon SM, Green CA, Kropp F, McHugh RK, et al. Substance abuse treatment entry, retention, and outcome in women: a review of the literature. Drug Alcohol Depend. 2007;86(1):1–21
  17. McLellan AT, Luborsky L, O'Brien CP, Barr HL, Evans F. Alcohol and drug abuse treatment in three different populations: is there improvement and is it predictable?. Am J Drug Alcohol Abuse. 1986;12(1-2):101–120
  18. Kreek MJ, Koob GF. Drug dependence: stress and dysregulation of brain reward pathways. Drug Alcohol Depend. 1998;51(1-2):23–47
  19. Piazza PV, Le Moal ML. Pathophysiological basis of vulnerability to drug abuse: role of an interaction between stress, glucocorticoids, and dopaminergic neurons. Annu Rev Pharmacol Toxicol. 1996;36:359–378
  20. Roberts ME, Moore SD, Beckham JC, Al'Absi M. Post-traumatic stress disorder and substance use disorders. In: Stress and Addiction: Biological and Psychological Mechanisms. San Diego, CA: Elsevier Academic Press; 2007;p. 315–331
  21. Spaccarelli S. Stress, appraisal, and coping in child sexual abuse: a theoretical and empirical review. Psychol Bull. 1994;116(2):340–362
  22. Ouimette PC, Ahrens C, Moos RH, Finney JW. Posttraumatic stress disorder in substance abuse patients: relationship to 1-year posttreatment outcomes. Psychol Addict Behav. 1997;11(1):34–47
  23. Ouimette P, Ahrens C, Moos R, Finney J. During treatment changes in substance abuse patients with posttraumatic stress disorder. The influence of specific interventions and program environments. J Subst Abuse Treat. 1998;15(7):555–564
  24. Ouimette PC, Finney JW, Moos RH. Two-year posttreatment functioning and coping of substance abuse patients with posttraumatic stress disorder. Psychol Addict Behav. 1999;13(2):105–114
  25. Haller DL, Knisely JS, Dawson KS, Schnoll SH. Perinatal substance abusers: psychological and social characteristics. J Nerv Ment Dis. 1993;181(8):509–513
  26. Kissin WB, Svikis DS, Morgan GD, Haug NA. Characterizing pregnant drug-dependent women in treatment and their children. J Subst Abuse Treat. 2001;21(1):27–34
  27. Hans SL. Demographic and psychosocial characteristics of substance-abusing pregnant women. Clin Perinatol. 1999;26:55–74
  28. Killeen TK, Brady KT, Thevos A. Addiction severity, psychopathology and treatment compliance in cocaine-dependent mothers. J Addict Dis. 1995;14(1):75–84
  29. Svikis D, Haug N, Lee J, Timpson R, Stitzer M, Rutigliano P. Predictors of treatment participation and retention in an intensive outpatient program for pregnant drug abusing women. In:  Harris LS editors. National Institute on Drug Abuse Research Monograph Series 162. Rockville, MD: National Institutue on Drug Abuse; 1996;p. 351
  30. Haug NA, Svikis DS, Diclemente C. Motivational enhancement therapy for nicotine dependence in methadone-maintained pregnant women. Psychol Addict Behav. 2004;18(3):289–292
  31. Jones HE, Haug NA, Stitzer ML, Svikis DS. Improving treatment outcomes for pregnant drug-dependent women using low-magnitude voucher incentives. Addict Behav. 2000;25(2):263–267
  32. Jones HE, Haug N, Silverman K, Stitzer M, Svikis D. The effectiveness of incentives in enhancing treatment attendance and drug abstinence in methadone-maintained pregnant women. Drug Alcohol Depend. 2001;61(3):297–306
  33. McLellan AT, Kushner H, Metzger D, Peters R, Smith I, Grissom G, et al. The fifth edition of the Addiction Severity Index. J Subst Abuse Treat. 1992;9(3):199–213
  34. McLellan AT, Luborsky L, Cacciola J, Griffith J, Evans F, Barr HL, et al. New data from the Addiction Severity Index: reliability and validity in three centers. J Nerv Ment Dis. 1985;173(7):412–423
  35. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured clinical interview for DSM-IV Axis I disorders. New York, NY: Biometrics Research; 1996;
  36. Skre I, Onstad S, Torgersen S, Kringlen E. High interrater reliability for the Structured Clinical Interview for DSM-III-R Axis I (SCID-I). Acta Psychiatr Scand. 1991;84(2):167–173
  37. Williams JB, Gibbon M, First MB, Spitzer RL, Davies M, Borus J, et al. The Structured Clinical Interview for DSM-III-R (SCID). II. Multisite test-retest reliability. Arch Gen Psychiatry. 1992;49(8):630–636
  38. Cacciola JS, Koppenhaver JM, McKay JR, Alterman AI. Test-Retest reliability of the lifetime items on the Addiction Severity Index. Psychol Assess. 1999;11(1):86–93
  39. Hosmer DW, Lemeshow S. Applied logistic regression. 2nd ed.. New York, NY: Wiley; 2000;
  40. Miller GA, Chapman JP. Misunderstanding analysis of covariance. J Abnorm Psychol. 2001;110(1):40–48
  41. Mills KL, Teesson M, Ross J, Peters L. Trauma, PTSD, and substance use disorders: findings from the Australian National Survey of Mental Health and Well-Being. Am J Psychiatry. 2006;163(4):652–658
  42. Ouimette P, Brown P, Najavits L. Course and treatment of patients with both substance use and posttraumatic stress disorders. Addict Behav. 1998;23(6):785–795
  43. Moos RH. Theory-based processes that promote the remission of substance use disorders. Clin Psychol Rev. 2007;27(5):537–551
  44. Amaro H, Dai J, Arevalo S, Acevedo A, Matsumoto A, Nieves R, et al. Effects of integrated trauma treatment on outcomes in a racially/ethnically diverse sample of women in urban community-based substance abuse treatment. J Urban Health. 2007;84(4):508–522
  45. Morrissey JP, Jackson EW, Ellis AR, Amaro H, Brown VB, Najavits LM. Twelve-month outcomes of trauma-informed interventions for women with co-occurring disorders. Psychiatr Serv. 2005;56(10):1213–1222
  46. Sher KJ, Trull TJ. Personality and disinhibitory psychopathology: Alcoholism and antisocial personality disorder. J Abnorm Psychol. 1994;103(1):92–102
  47. Verheul R. Co-morbidity of personality disorders in individuals with substance use disorders. Eur Psychiatry. 2001;16(5):274–282

PII: S0010-440X(08)00170-3

doi: 10.1016/j.comppsych.2008.11.004

Comprehensive Psychiatry
Volume 50, Issue 5 , Pages 415-423 , September 2009

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