Relationship between insight and neurocognition in patients with bipolar I disorder in remission

Yen, Cheng-Fang; Cheng, Chung-Ping; Ko, Chih-Hung; Yen, Ju-Yu; Huang, Chi-Fen; Chen, Cheng-Sheng

doi:10.1016/j.comppsych.2007.12.006

« Previous Next »Comprehensive Psychiatry
Volume 49, Issue 4 , Pages 335-339, July 2008

Relationship between insight and neurocognition in patients with bipolar I disorder in remission

Cheng-Fang Yen
- Department of Psychiatry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City 807, Taiwan
- Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan
Chung-Ping Cheng
- Department of Psychology and Research Center for Mind, Brain, and Learning, National Chengchi University, Taipei City 116, Taiwan
Chih-Hung Ko
- Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan
- Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City 807, Taiwan
Ju-Yu Yen
- Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan
- Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City 807, Taiwan
- Department of Psychiatry, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung City 812, Taiwan
Chi-Fen Huang
- Department of Psychiatry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City 807, Taiwan
Cheng-Sheng Chen
- Department of Psychiatry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City 807, Taiwan
- Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan
- Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City 807, Taiwan
- Corresponding author. Department of Psychiatry, Kaohsiung Medical University, Kaohsiung 807, Taiwan. Tel.: +886 7 3121101x6822; fax: +886 7 3134761.

published online 20 March 2008.

Abstract

The aim of this study was to examine the relationships between insight and neurocognition in a population of patients with bipolar I disorder who were in a remitted state. Using the Schedule of Assessment of Insight (SAI) and its expanded version, we evaluated 96 patients with bipolar I disorder in remission to determine their level of insight. We also evaluated their neurocognitive function included in the domains of executive function, attention, and memory. The associations between insight and neurocognitive function were examined by using the stepwise multiple regression analysis to control the confounding effects of sociodemographic and clinical factors. The results indicated that by controlling the confounding effects of other factors, executive function was positively associated with the SAI dimensions of awareness of illness and relabeling of phenomena, and the total expanded version of the SAI in remitted bipolar patients. The results of this study indicated that the relationships vary between different dimensions of insight and domains of neurocognitive function in remitted bipolar patients.