Course of obsessive-compulsive disorder during early postpartum period: a prospective analysis of 16 cases

Uguz, Faruk; Gezginc, Kazim; Zeytinci, Ismet Esra; Karatayli, Savas; Askin, Rustem; Guler, Ozkan; Sahin, Figen Kir; Emul, H. Murat; Ozbulut, Omer; Gecici, Omer

doi:10.1016/j.comppsych.2007.05.010

« Previous Next »Comprehensive Psychiatry
Volume 48, Issue 6 , Pages 558-561, November 2007

Course of obsessive-compulsive disorder during early postpartum period: a prospective analysis of 16 cases

Faruk Uguz
- Department of Psychiatry, Meram Faculty of Medicine, Selçuk University, 42080 Konya, Turkey
- Corresponding author. Selçuk Universities, Meram Tip Fakultesi Psikiyatri, Anabilim Dali, 42080 Konya, Turkey. Tel.: +90 332 236837.
Kazim Gezginc
- Department of Obstetrics and Gynecology, Meram Faculty of Medicine, Selçuk University, 42080 Konya, Turkey
Ismet Esra Zeytinci
- Department of Psychiatry, Meram Faculty of Medicine, Selçuk University, 42080 Konya, Turkey
Savas Karatayli
- Department of Psychiatry, Meram Faculty of Medicine, Selçuk University, 42080 Konya, Turkey
Rustem Askin
- Department of Psychiatry, Meram Faculty of Medicine, Selçuk University, 42080 Konya, Turkey
Ozkan Guler
- Department of Psychiatry, Faculty of Medicine, Kocatepe University, Afyon 03200, Turkey
Figen Kir Sahin
- Department of Psychiatry, Faculty of Medicine, Kocatepe University, Afyon 03200, Turkey
H. Murat Emul
- Department of Psychiatry, Faculty of Medicine, Kocatepe University, Afyon 03200, Turkey
Omer Ozbulut
- Department of Psychiatry, Faculty of Medicine, Kocatepe University, Afyon 03200, Turkey
Omer Gecici
- Department of Psychiatry, Faculty of Medicine, Kocatepe University, Afyon 03200, Turkey

published online 20 August 2007.

Abstract

Objective

The aim of the current study was to prospectively examine a course of obsessive-compulsive disorder (OCD) during the early postpartum period.

Method

The study data were collected from 16 pregnant women with a diagnosis of OCD according to the Structured Clinical Interview for DSM-IV (SCID-I). Obsessive-compulsive disorder symptoms were assessed by the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) before and after childbirth. Psychopharmacologic or psychotherapeutic treatments were not administered over the study period.

Results

Scores of the mean Y-BOCS-total and Y-BOCS-obsession were significantly reduced from the basal levels to 6 weeks postnatally. No significant difference was found in terms of Y-BOCS-compulsion between 2 interviews. During the study period, whereas the Y-BOCS-total scores were decreased by at least 25% in 8 (50.0%) of 16 patients, only 1 (6.2%) of 16 patients experienced at least a 25% increase in the same scores.