Comprehensive Psychiatry
Volume 48, Issue 2 , Pages 155-160 , March 2007

Quality of life and functioning ability in subjects vulnerable to psychosis

  • Tanja Svirskis

      Affiliations

    • Department of Psychiatry, University of Turku, 20700 Turku, Finland
    • Psychiatric Clinic, Turku University Central Hospital, 20520 Turku, Finland
    • Corresponding Author InformationCorresponding author. Department of Psychiatry, University of Turku, 20700 Turku, Finland. Tel.: + 358 2 269 2285; fax: +358 2 269 2528.
    • ,
  • Jyrki Korkeila

      Affiliations

    • Department of Psychiatry, University of Turku, 20700 Turku, Finland
    • Turku Psychiatric Clinic, Turku Mental Health Centre, 20700 Turku, Finland
    • ,
  • Markus Heinimaa

      Affiliations

    • Department of Psychiatry, University of Turku, 20700 Turku, Finland
    • ,
  • Jukka Huttunen

      Affiliations

    • Department of Psychiatry, University of Turku, 20700 Turku, Finland
    • Turku Psychiatric Clinic, Turku Mental Health Centre, 20700 Turku, Finland
    • ,
  • Tuula Ilonen

      Affiliations

    • Department of Psychiatry, University of Turku, 20700 Turku, Finland
    • ,
  • Terja Ristkari

      Affiliations

    • Department of Psychiatry, University of Turku, 20700 Turku, Finland
    • ,
  • Jarmo Hietala

      Affiliations

    • Department of Psychiatry, University of Turku, 20700 Turku, Finland
    • Turku Psychiatric Clinic, Turku Mental Health Centre, 20700 Turku, Finland
    • Turku PET Centre, Turku University Central Hospital, 20520 Turku, Finland
    • ,
  • Erkka Syvälahti

      Affiliations

    • Department of Psychopharmacology, University of Turku, 20520 Turku, Finland
    • ,
  • Thomas McGlashan

      Affiliations

    • Department of Psychiatry, Yale University, New Haven, CT 06159, USA
    • ,
  • Tero Vahlberg

      Affiliations

    • Department of Biostatistics, University of Turku, 20520 Turku, Finland
    • ,
  • Raimo K.R. Salokangas

      Affiliations

    • Department of Psychiatry, University of Turku, 20700 Turku, Finland
    • Psychiatric Clinic, Turku University Central Hospital, 20520 Turku, Finland
    • Turku Psychiatric Clinic, Turku Mental Health Centre, 20700 Turku, Finland

References 

  1. Katsching H. Schizophrenia and quality of life. Acta Psychiatr Scand. 2000;102(Suppl 407):33–37
  2. Bechdolf A, Pukrop R, Köhn D, Tschinkel S, Veith V, Schulze-Lutter F, et al. Subjective quality of life in persons at high-risk for a first episode psychosis: a comparison with first episode schizophrenia patients and healthy controls. Schizophr Res. 2005;79:137–143
  3. Yung AR, Phillips LJ, Yen HP, McGorry PD. Risk factors for psychosis in an ultra high-risk group: psychopathology and clinical features. Schizophr Res. 2003;67:131–142
  4. Ruhrman S, Schulze-Lutter F, Wieneke A, Picker H, Pukrop R, Hoppmann B. Do patients with a prodromal syndrome cross the threshold of clinical illness?. Schizophr Res. 2004;70(Suppl):37–38
  5. Davidson M, Reichenberg MA, Rabinowitz J, Weiser M, Kaplan Z, Mark M. Behavioral and intellectual markers for schizophrenia in apparently healthy male adolescents. Am J Psychiatry. 1999;156:1328–1335
  6. Häfner H, Löffler W, Maurer K, Hambrecht M, an der Heiden W. Depression, negative symptoms, social stagnation and social decline in the early course of schizophrenia. Acta Psychiatr Scand. 1999;100:105–118
  7. Cornblatt BA, Lencz T, Smith CW, Correll CU, Auther AM, Nakayama E. The schizophrenia prodrome revisited; a neurodevelopmental perspective. Sch Bull. 2003;4(29):633–651
  8. Rabinowitz J, Haim R, Reichenberg A, Weiser M, Kaplan Z, Davidson M, et al. Association between functioning in adolescence prior to first admission for schizophrenia and affective disorders and patterns of hospitalizations thereafter. Schizophr Res. 2005;73:185–191
  9. Pinikahana J, Happel B, Hope J, Keks NA. Quality of life in schizophrenia: a review of literature from 1995-2000. Int J Ment Health Nurs. 2002;11:103–111
  10. Lambert M, Naber D. Current issues in schizophrenia: overview of patient acceptability, functioning capacity and quality of life. CNS Drugs. 2004;18(Suppl 2):5–7[discussion 41-3]
  11. Norman RMG, Malla AK, McLean T, Voruganti LPN, Cortese L, McIntosh E, et al. The relationship of symptoms and level of functioning in schizophrenia to general wellbeing and Quality of Life Scale. Acta Psychiatr Scand. 2000;102:303–309
  12. Wegener S, Redoblado-Hodge MA, Lucas S, Fitzgerald D, Harris A, Brennan J. Relative contributions of psychiatric symptoms and neuropsychological functioning to quality of life in first-episode psychosis. Aust N Z J Psychiatry. 2005;39:487–492
  13. Salokangas RKR, Heinimaa M, Ilonen T, Suomela T, Korkeila J, Plathin M, et al. Epidemiology of prodrome in familial schizophrenia. In:  Millet T, et al. editor. Early intervention in psychiatric disorders. Dordrecht, the Netherlands: Kluwer Academic Publishers; 2001;p. 47–69
  14. Salokangas RKR, Heinimaa M, Ilonen T, Suomela T, Korkeila J, Plathin M, et al. Vulnerability to and risk of psychosis. Description, experiences and preliminary results of the Detection of Early Psychosis or DEEP project. Neurol Psychiatry Brain Res. 2004;11:37–44
  15. Miller T, McGlashan T, Woods S, Stein K, Driesen N, Corcoran C, et al. Symptom assessment in schizophrenic prodromal states. Psychiatr Q. 1999;70:273–289
  16. American Psychiatric Association . DSM-IV: diagnostic and statistical manual of mental disorders. 4th ed.. Washington (DC): American Psychiatric Association; 1994;
  17. Heinrichs D, Hanlon T, Carpenter W. The Quality of Life Scale: an instrument for rating the schizophrenia deficit syndrome. Schizophr Bull. 1984;10(3):388–398
  18. Svirskis T, Korkeila J, Heinimaa M, Huttunen J, Ilonen T, Ristkari T, et al. Axis-I disorders and vulnerability to psychosis. Schizophr Res. 2005;75:439–446
  19. Zubin J, Spring B. Vulnerability—a new view of schizophrenia. J Abnorm Psychol. 1977;82:103–126
  20. Pukrop R, Möller HJ, Steinmeyer EM. Quality of life in psychiatry. A systematic contribution to construct validation and development of the integrative assessment tool. Modular system of quality of life. Eur Arch Psychiatry Clin Neurosci. 2000;250:120–132
  21. Mason O, Startup M, Halpin S, Schall U, Conrad A, Carr V. Risk factors for transition to first episode psychosis among individuals with “at-risk mental states”. Schizophr Res. 2004;71:227–237
  22. McGorry P, Yung A, Phillips L, Yuen H, Francey S, Cosgrave E, et al. Randomised controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms. Arch Gen Psychiatry. 2002;59:921–928
  23. Miller TJ, Zipursky RB, Perkins D, Addington J, Woods SW, Hawkins KA, et al. The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis: II. Baseline characteristics of the “prodromal” sample. Schizophr Res. 2003;61:19–30
  24. Browne S, Roe M, Lane A, Gervin M, Morris M, Kinsella A, et al. Quality of life in schizophrenia: relationships to sociodemographic factors, symptomatology and tardive dyskinesia. Acta Psychiatr Scand. 1996;94:118–124
  25. Milev P, Ho B-C, Arndt S, Andreasen N. Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: a longitudinal first-episode study with 7-year follow-up. Am J Psychiatry. 2005;162:495–506
  26. Salokangas RKR, Räkköläinen V, Alanen YO. Maintenance of grip of life and goals of life: a valuable criterion for evaluating outcome in schizophrenia. Acta Psychiatr Scand. 1989;80:187–193
  27. Kay SR. The positive and negative symptom scale (PANSS) of schizophrenia. Schizophr Bull. 1987;13:261–276

PII: S0010-440X(06)00126-X

doi: 10.1016/j.comppsych.2006.10.008

Comprehensive Psychiatry
Volume 48, Issue 2 , Pages 155-160 , March 2007

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