Comprehensive Psychiatry
Volume 47, Issue 2 , Pages 91-98 , March 2006

Is major depressive episode related to anxiety disorders in anorexics and bulimics?

  • Nathalie T. Godart

      Affiliations

    • Department of Psychiatry, Institut Mutualiste Montsouris (IMM), Université Paris V Paris, Unité INSERM U 669 PSIGIAM, France
    • Corresponding Author InformationCorresponding author. Department of Psychiatry, Institut Mutualiste Montsouris, 75014 Paris, France. Tel.: +33 1 56 61 69 35; fax: +33 1 56 61 69 34.
  • ,
  • Fabienne Perdereau

      Affiliations

    • Department of Psychiatry, Institut Mutualiste Montsouris (IMM), Université Paris V Paris, Unité INSERM U 669 PSIGIAM, France
  • ,
  • Florence Curt

      Affiliations

    • Department of Psychiatry, Institut Mutualiste Montsouris (IMM), Université Paris V Paris, Unité INSERM U 669 PSIGIAM, France
  • ,
  • Zoé Rein

      Affiliations

    • Department of Psychiatry, Institut Mutualiste Montsouris (IMM), Université Paris V Paris, Unité INSERM U 669 PSIGIAM, France
  • ,
  • François Lang

      Affiliations

    • Department of Psychiatry, Centre Hospitalier Universitaire de Saint Etienne, France
  • ,
  • Jean Luc Venisse

      Affiliations

    • Department of Psychiatry, Hôpital Saint Jacques–Unité des addictionsNantes
  • ,
  • Olivier Halfon

      Affiliations

    • Service universitaire de Psychiatrie de l'enfant et de l'adolescent Lausanne–Suisse
  • ,
  • Paul Bizouard

      Affiliations

    • Department of Psychiatry, Centre Hospitalier Universitaire de Besançon, France
  • ,
  • Gwenole Loas

      Affiliations

    • Department of Psychiatry, Secteur Hospitalo–Universitaire P. Pinel Amiens, France
  • ,
  • Maurice Corcos

      Affiliations

    • Department of Psychiatry, Institut Mutualiste Montsouris (IMM), Université Paris V Paris, Unité INSERM U 669 PSIGIAM, France
  • ,
  • Philippe Jeammet

      Affiliations

    • Department of Psychiatry, Institut Mutualiste Montsouris (IMM), Université Paris V Paris, Unité INSERM U 669 PSIGIAM, France
  • ,
  • Martine F. Flament

      Affiliations

    • Department of Psychiatry, University of Ottawa, Royal Ottawa Hospital, Ontario, Canada

References 

  1. Iwasaki Y, Matsunaga H, Kiriike N, Tanaka H, Matsui T. Comorbidity of axis I disorders among eating-disordered subjects in Japan. Compr Psychiatry. 2000;41(6):454–460
  2. Herzog DB, Dorer DJ, Keel PK, Selwyn SE, Ekeblad ER, Flores AT, et al. Recovery and relapse in anorexia and bulimia nervosa: a 7.5-year follow-up study. J Am Acad Child Adolesc Psychiatry. 1999;38(7):829–837
  3. Hudson JI, Pope HGJ, Yurgelun TD, Jonas JM, Frankenburg FR. A controlled study of lifetime prevalence of affective and other psychiatric disorders in bulimic outpatients. Am J Psychiatry. 1987;144(10):1283–1287
  4. Hudson JI, Pope HGJ, Yurgelun TD. Bulimia and major affective disorder: experience with 105 patients. Psychiatr Psychobiol. 1988;3:37–47
  5. Brewerton TD. Toward a unified theory of serotonin dysregulation in eating and related disorders. Psychoneuroendocrinology. 1995;20(6):561–590
  6. Schwalberg MD, Barlow DH, Alger SA, Howard LJ. Comparison of bulimics, obeses, binge eaters, social phobics and individuals with panic disorders on comorbidity across DSM-III-R anxiety disorders. J Abnorm Psychol. 1992;101:4675–4681
  7. Godart NT, Flament MF, Lecrubier Y, Jeammet P. Anxiety disorders in anorexia nervosa and bulimia nervosa: co-morbidity and chronology of appearance. Eur Psychiatry. 2000;15(1):38–45
  8. Laessle RG, Wittchen HU, Fichter MM, Pirke KM. The significance of subgroups of bulimia and anorexia nervosa: life time frequency of psychiatric disorders. Int J Eat Disord. 1989;8:569–574
  9. Angst J. Depression and anxiety: implications for nosology, course, and treatment. J Clin Psychiatry. 1997;58(Suppl 8):3–5
  10. Roy-Byrne PP, Stang P, Wittchen HU, Ustun B, Walters EE, Kessler RC. Lifetime panic-depression comorbidity in the National Comorbidity Survey. Association with symptoms, impairment, course and help-seeking. Br J Psychiatry. 2000;176:229–235
  11. Sanderson WC, Beck AT, Beck J. Syndrome comorbidity in patients with major depression or dysthymia: prevalence and temporal relationships. Am J Psychiatry. 1990;147(8):1025–1028
  12. Guelfi JD. La comorbidité anxiété-dépression et son traitement. Encéphale. 1993;19:397–404
  13. Zajecka JM, Ross JS. Management of comorbid anxiety and depression. J Clin Psychiatry. 1995;56(Suppl 2):10–13
  14. Wittchen HU, Essau CA. Comorbidity and mixed anxiety-depressive disorders: is there epidemiologic evidence?. J Clin Psychiatry. 1993;54(Suppl):9–15
  15. Liebowitz MR, Hollander E, Schneier F, Campeas R, Fallon B, Welkowitz L, et al. Anxiety and depression: discrete diagnostic entities?. J Clin Psychopharmacol. 1990;10(3 Suppl):61S–66S
  16. Brawman-Mintzer O, Lydiard RB, Emmanuel N, Payeur R, Johnson M, Roberts J, et al. Psychiatric comorbidity in patients with generalized anxiety disorder. Am J Psychiatry. 1993;150(8):1216–1218
  17. Stein MB, McQuaid JR, Pedrelli P, Lenox R, McCahill ME. Posttraumatic stress disorder in the primary care medical setting. Gen Hosp Psychiatry. 2000;22(4):261–269
  18. Weissman MM, Bland RC, Canino GJ, Greenwald S, Hwu HG, Lee CK, et al. The cross national epidemiology of obsessive compulsive disorder. The Cross National Collaborative Group. J Clin Psychiatry. 1994;55(Suppl):5–10
  19. Wittchen HU, Hoyer J. Generalized anxiety disorder: nature and course. J Clin Psychiatry. 2001;62(Suppl 11):15–19
  20. Bulik CM, Sullivan PF, Carter FA, Joyce PR. Lifetime anxiety disorders in women with bulimia nervosa. Compr Psychiatry. 1996;37(5):368–374
  21. Kovess V. Epidémiologie des comorbidités psychiatriques dans la dépression. In:  Lempérière Th editors. Dépressions et comorbidités psychiatriques. Paris: Masson; 2001;p. 27–50
  22. Godart NT, Flament MF, Perdereau F, Jeammet P. Comorbidity between eating disorders and mood disorders: review. 2002;[submitted for publication]
  23. Kendall PC, Kortlander E, Chansky TE, Brady EU. Comorbidity of anxiety and depression in youth: treatment implications. J Consult Clin Psychol. 1992;60(6):869–880
  24. Keys A, Brozek J, Henschel A, Mickelsen O, Taylor HL. The biology of human starvation. In: Minneapolis (MN): University of Minnesota Press; 1950;
  25. Flament MF, Corcos M, Guelfi JD, Bolognini M, Paterniti S, Perez-Diaz F, et al. Personality characteristics as risk factors for the addictive disorders: a comparative study of subjects with eating disorders, alcohol dependence and drug dependence, to normal controls. In: 5th International Congress of the International Society for Adolescent Psychiatry (ISAP), Aix-en-Provence, July 4-7. 1999;[personal communication]
  26. Godart NT, Flament MF, Jeammet P. Anxiety disorders and mood disorders comorbidity in patients with eating disorders: a multicentric comparative study. In: XIth World Congress of Psychiatry, Hamburg, August 6-11. 1999;[personal communication]
  27. Godart NT, Flament MF, Curt F, Perdereau F, Lang F, Venisse JL, et al. Anxiety disorders in subjects seeking treatment for eating disorders: a DSM-IV controlled study. Psychiatry Res. 2003;(117):245–258
  28. Lecrubier Y, Sheehan DV, Weiller E, Amorin P, Bonora I, Harnet Sheehan K, et al. The Mini International Neuropsychiatric Interview (MINI) a short diagnostic structured interview: reliability and validity according to the CIDI. Eur Psychiatry. 1999;12:224–231
  29. Sheehan DV, Lecrubier Y, Harnett Sheehan H, Janavs J, Weiller E, Keskiner A, et al. Reliability and validity of the Mini International Neuropsychiatric Interview (MINI) according to the SCIDP. Eur Psychiatry. 1999;12:232–241
  30. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, et al. The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59(Suppl 20):22–33
  31. APA. DSM-IV. Manuel diagnostique et statistique des troubles mentaux (Washington DC, 1994). Traduction française par J.D. Guelfi et al. Paris: Masson; 1996
  32. Rolland-Cachera MF, Cole TJ, Sempe M, Tichet J, Rossignol C, Charraud A. Body mass index variations: centiles from birth to 87 years. Eur J Clin Nutr. 1991;45(1):13–21
  33. Cochran WG. Some methods for strengthening the common chi-2. Tests Biometrics. 1954;10:417–451
  34. Lépine JP, Wittchen HU, Essau CA Participants of the WHO/ADAMHA CIDI field trials. Lifetime and current comorbidity of anxiety and depressive disorders: results from the WHO/ADAMHA CIDI field trials. Int J Methods Psychiatr Res. 1993;3:67–77
  35. Cloninger CR. Comorbidity of anxiety and depression. J Clin Psychopharmacol. 1990;10(3 Suppl):43S–46S
  36. Hantouche EG, Bouhassira M, Lancrenon S, Ravily V, Bourgeois M. Prevalence of obsessive-compulsive disorders in a large French patient population in psychiatric consultation. Encephale. 1995;21(5):571–580
  37. Stein MB, Chavira DA. Subtypes of social phobia and comorbidity with depression and other anxiety disorders. J Affect Disord. 1998;50(Suppl 1):S11–S16
  38. Keel PK, Dorer DJ, Eddy KT, Delinsky SS, Franko DL, Blais MA, et al. Predictors of treatment utilization among women with anorexia and bulimia nervosa. Am J Psychiatry. 2002;159(1):140–142
  39. Galès O. Facteurs déterminants du contrat de poids dans l'anorexie mentale: étude sur les liens entre les hypothèses théoriques et la réalité clinique Mémoire de DES sous la direction de N Godart. Paris; 2000;
  40. APA . Practice guideline for the treatment of patients with eating disorders (revision). American Psychiatric Association Work Group on Eating Disorders. Am J Psychiatry. 2000;157(1 Suppl):1–39
  41. Grunhaus L. Clinical and psychobiological characteristics of simultaneous panic disorder and major depression. Am J Psychiatry. 1988;145(10):1214–1221
  42. Wittchen HU, Essau CA. Epidemiology of panic disorder: progress and unresolved issues. J Psychiatr Res. 1993;27(Suppl 1):47–68
  43. Zaider TI, Johnson JG, Cockell SJ. Psychiatric comorbidity associated with eating disorder symptomatology among adolescents in the community. Int J Eat Disord. 2000;28(1):58–67
  44. Wittchen HU, Zhao HS, Kessler RC, Eaton WW. DSM-III-R general anxiety disorder in the National Comorbidity Survey. Arch Gen Psychiatry. 1994;51:355–364
  45. Hecht H, von Zerssen D, Wittchen HU. Anxiety and depression in a community sample: the influence of comorbidity on social functioning. J Affect Disord. 1990;18(2):137–144

 All authors disclose any financial conflict of interest.

PII: S0010-440X(05)00080-5

doi: 10.1016/j.comppsych.2005.07.001

Comprehensive Psychiatry
Volume 47, Issue 2 , Pages 91-98 , March 2006