Comprehensive Psychiatry
Volume 46, Issue 6 , Pages 405-416, November 2005

The AUDIT-C: screening for alcohol use disorders and risk drinking in the presence of other psychiatric disorders

Laboratory of Epidemiology and Biometry, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892-9304, USA

Abstract 

This article examines the performance of the AUDIT-C, as embedded in a large national survey, as a screener for alcohol use disorders (AUDs) and risk drinking among individuals with past-year psychopathology. The analysis is based on data collected in personal interviews from a representative population sample of US adults. The study population consisted of past-year drinkers with any past-year mood disorder (n = 2818), any past-year anxiety disorder (n = 3173), or any personality disorder (n = 4389). Screening performance was evaluated by means of sensitivity, specificity, and areas under receiver operating characteristic curves (AUCs). The AUCs for the AUDIT-C were from 0.888 to 0.893 for alcohol dependence, from 0.864 to 0.876 for any AUD, and from 0.941 to 0.951 for any AUD or risk drinking—all on a par with those observed in the general population. Among men, cut points of either ≥5 or ≥6 points (the former favoring sensitivity and the latter favoring specificity) were optimal for detecting dependence, and cut points of ≥5 points were optimal for any AUD and for any AUD or risk drinking. Among women, a cut point of ≥4 points was optimal for the outcomes of both alcohol dependence and any AUD, whereas a cut point of ≥3 points was preferable for detecting any AUD or risk drinking.

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 The study on which this article is based, the National Epidemiologic Survey on Alcohol and Related Conditions, is sponsored by the National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, US Department of Health and Human Services, with supplemental support from the National Institute on Drug Abuse.

PII: S0010-440X(05)00018-0

doi:10.1016/j.comppsych.2005.01.006

Comprehensive Psychiatry
Volume 46, Issue 6 , Pages 405-416, November 2005