Comprehensive Psychiatry
Volume 46, Issue 4 , Pages 278-283 , July 2005

Health-related quality of life and psychiatric comorbidity in first episode psychosis

  • Kang Sim

      Affiliations

    • Corresponding Author InformationCorresponding author. Schizophrenia and Bipolar Disorders Program (AB347), McLean Hospital/Harvard Medical School, Belmont, MA 02478, USA. Tel.: +65 617 8552961; fax: +65 617 8552895.
    • Department of Early Psychosis Intervention, Woodbridge Hospital/Institute of Mental Health, Singapore 539747, Republic of Singapore
    • Schizophrenia and Bipolar Disorders Program (AB347), McLean Hospital/Harvard Medical School, Belmont, MA 02478, USA
    • Department of Adult Psychiatry, Woodbridge Hospital/ Institute of Mental Health, Singapore, Republic of Singapore
  • ,
  • Rathi Mahendran

      Affiliations

    • Department of Adult Psychiatry, Woodbridge Hospital/ Institute of Mental Health, Singapore, Republic of Singapore
  • ,
  • Siow Ann Chong

      Affiliations

    • Department of Early Psychosis Intervention, Woodbridge Hospital/Institute of Mental Health, Singapore 539747, Republic of Singapore

References 

  1. Leplege A, Hunt S. The problem of quality of life in medicine. JAMA. 1997;278:47–50
  2. Lehman AF. Measures of quality of life among persons with severe and persistent mental disorders. Soc. Psychiatry Psychiatr. Epidemiol. 1996;31:78–88
  3. Awad AG, Voruganti LN, Heslegrave RJ. Measuring quality of life in patients with schizophrenia. PharmacoEconomics. 1997;11:32–47
  4. Wilson IB, Cleary PD. Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. JAMA. 1995;273:59–65
  5. Saxena S, Carlson D, Billington R. The WHO quality of life assessment instrument (WHOQOL-Bref): the importance of its items for cross-cultural research. Qual. Life Res. 2001;10:711–721
  6. Corrigan PW, Buican B. The construct validity of subjective quality of life for the severely mentally ill. J. Nerv. Ment. Dis. 1995;183:281–285
  7. Atkinson M, Zibin S, Chuang H. Characterizing quality of life among patients with chronic mental illness: a critical examination of the self-report methodology. Am. J. Psychiatry. 1997;154:99–105
  8. Koivumaa-Honkanen HT, Honkanen R, Antikainen R, Hintikka J, Viinamaki H. Self-reported life satisfaction and treatment factors in patients with schizophrenia, major depression and anxiety disorder. Acta Psychiatr. Scand. 1999;99:377–384
  9. Lehman AF. A quality of life interview for the chronically mentally ill. Eval. Program Plann. 1988;11:51–52
  10. Pinkney AA, Gerber GJ, Lafave HG. Quality of life after psychiatric rehabilitation: the clients' perspective. Acta Psychiatr. Scand. 1991;83:86–91
  11. Sullivan G, Wells KB, Leake B. Quality of life of seriously mentally ill persons in Mississippi. Hosp. Community Psychiatry. 1991;42:752–755
  12. Barry MM, Crosby C. Quality of life as an evaluative measure in assessing the impact of community care on people with long-term psychiatric disorders. Br. J. Psychiatry. 1996;168:210–216
  13. Institute of Medicine. Crossing the quality chasm: a new health system for the 21st century. Washington (DC): Institute of Medicine; 2001;
  14. Norman RM, Malla AK, McLean T, et al. The relationship of symptoms and level of functioning in schizophrenia to general wellbeing and the Quality of Life Scale. Acta Psychiatr. Scand. 2000;102:303–309
  15. Voruganti L, Heslegrave R, Awad AG, Seeman MV. Quality of life measurement in schizophrenia: reconciling the quest for subjectivity with the question of reliability. Psychol. Med. 1998;28:165–172
  16. Angermeyer MC, Holzinger A, Kilian R, Matschinger H. Quality of life-as defined by schizophrenic patients and psychiatrists. Int. J. Soc. Psychiatry. 2001;47:34–42
  17. Herrman H, Hawthorne G, Thomas R. Quality of life assessment in people living with psychosis. Soc. Psychiatry Psychiatr. Epidemiol. 2002;37:510–518
  18. Olusina AK, Ohaeri JU. Subjective quality of life of recently discharged Nigerian psychiatric patients. Soc. Psychiatry Psychiatr. Epidemiol. 2003;38:707–714
  19. Lehman AF. The well-being of chronic mental patients. Arch. Gen. Psychiatry. 1983;40:369–373
  20. Skantze K, Malm U, Dencker SJ, May PR, Corrigan P. Comparison of quality of life with standard of living in schizophrenic out-patients. Br. J. Psychiatry. 1992;161:797–801
  21. Wetherell JL, Palmer BW, Thorp SR, Patterson TL, Golshan S, Jeste DV. Anxiety symptoms and quality of life in middle-aged and older outpatients with schizophrenia and schizoaffective disorder. J. Clin. Psychiatry. 2003;64:1476–1482
  22. Huppert JD, Smith TE. Longitudinal analysis of subjective quality of life in schizophrenia: anxiety as the best symptom predictor. J. Nerv. Ment. Dis. 2001;189:669–675
  23. Strakowski SM, Tohen M, Stoll AL, Faedda GL, Mayer PV, Kolbrener ML, et al. Comorbidity in psychosis at first hospitalization. Am. J. Psychiatry. 1993;150:752–757
  24. Sim K, Swapna V, Mythily S, et al. Psychiatric comorbidity in first episode psychosis: the Early Psychosis Intervention Program (EPIP) experience. Acta Psychiatr. Scand. 2004;109:23–29
  25. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM IV Axis I Disorders, Patient edition (SCID-P), version 2. New York: New York State Psychiatric Institute, Biometrics Research; 1994;
  26. Hasin DS, Skodol AE. Standardised diagnostic interviews for psychiatric research. In:  Thompson C editors. The instruments of psychiatric research. New York: John Wiley and Sons; 1989;p. 37–42
  27. Segal DL, Hersen M, Van Hasselt VB. Reliability of the structured clinical interview for DSM III R: an evaluative review. Compr. Psychiatry. 1994;35:316–332
  28. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed.. Washington: American Psychiatric Association; 1994;
  29. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr. Bull. 1987;13:261–276
  30. Amador XF, Flaum M, Andreasen NC, et al. Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch. Gen. Psychiatry. 1994;51:826–836
  31. WHOQOL Group. Development of the World Health Organization WHOQOL-BREF quality of life assessment. Psychol. Med. 1998;28:551–558
  32. Yao G, Chung CW, Yu CF, Wang JD. Development and verification of validity and reliability of the WHOQOL-BREF Taiwan version. J. Formos. Med. Assoc. 2002;101:342–351
  33. Cassano GB, Pini S, Saettoni M, Rucci P, Dell'Osso L. Occurrence and clinical correlates of psychiatric comorbidity in patients with psychotic disorders. J. Clin. Psychiatry. 1998;59:60–68
  34. Dickerson FB, Ringel NB, Parente F. Subjective quality of life in out-patients with schizophrenia: clinical and utilization correlates. Acta Psychiatr. Scand. 1998;98:124–127
  35. Priebe S, Roeder-Wanner UU, Kaiser W. Quality of life in first-admitted schizophrenia patients: a follow-up study. Psychol. Med. 2000;30:225–230
  36. Zissi A, Barry MM, Cochrane R. A mediational model of quality of life for individuals with severe mental health problems. Psychol. Med. 1998;28:1221–1230
  37. Smith TE, Hull JW, Israel LM, Willson DF. Insight, symptoms, and neurocognition in schizophrenia and schizoaffective disorder. Schizophr. Bull. 2000;26:193–200
  38. Drake RJ, Pickles A, Bentall RP, Kinderman P, Haddock G, Tarrier N, et al. The evolution of insight, paranoia and depression during early schizophrenia. Psychol. Med. 2004;34:285–292
  39. Iqbal Z, Birchwood M, Chadwick P, Trower P. Cognitive approach to depression and suicidal thinking in psychosis. 2. Testing the validity of a social ranking model. Br. J. Psychiatry. 2000;177:522–528
  40. Ritsner M, Modai I, Endicott J, et al. Differences in quality of life domains and psychopathologic and psychosocial factors in psychiatric patients. J. Clin. Psychiatry. 2000;61:880–889
  41. Carpiniello B, Lai GL, Pariante CM, Carta MG, Rudas N. Symptoms, standards of living and subjective quality of life: a comparative study of schizophrenic and depressed out-patients. Acta Psychiatr. Scand. 1997;96:235–241
  42. Ho BC, Andreasen NC, Flaum M, Nopoulos P, Miller D. Untreated initial psychosis: its relation to quality of life and symptom remission in first-episode schizophrenia. Am. J. Psychiatry. 2000;157:808–815
  43. Sainfort F, Becker M, Diamond R. Judgments of quality of life of individuals with severe mental disorders: patient self-report versus provider perspectives. Am. J. Psychiatry. 1996;153:497–502
  44. Khatri N, Romney DM, Pelletier G. Validity of self-reports about quality of life among patients with schizophrenia. Psychiatr. Serv. 2001;52:534–535
  45. Galletly CA, Clark CR, McFarlane AC, Weber DL. Relationships between changes in symptom ratings, neurophysiological test performance and quality of life in schizophrenic patients treated with clozapine. Psychiatry Res. 1997;72:161–166
  46. Browne S, Clarke M, Gervin M, Waddington JL, Larkin C, O'Callaghan E. Determinants of quality of life at first presentation with schizophrenia. Br. J. Psychiatry. 2000;176:173–176
  47. Pukrop R, Moller HJ, Steinmeyer EM. Quality of life in psychiatry: a systematic contribution to construct validation and the development of the integrative assessment tool “modular system for quality of life”. Eur. Arch. Psychiatry Clin. Neurosci. 2000;250:120–132

PII: S0010-440X(04)00176-2

doi: 10.1016/j.comppsych.2004.11.001

Comprehensive Psychiatry
Volume 46, Issue 4 , Pages 278-283 , July 2005