Comprehensive Psychiatry
Volume 44, Issue 6 , Pages 462-465 , November 2003

Twenty-year behavioral follow-up of a 1;13 chromosomal translocation and mobius syndrome presenting with poor impulse control, exhibitionism, and aggression

  • Dawson W Hedges

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Dawson Hedges, M.D., Department of Psychology, 1001 SWKT, Brigham Young University, Provo, UT 84602, USA
    • Department of Psychology and the Neuroscience Center, Brigham Young University, Provo, Utah, USA
    • ,
  • Kreg G Jeppson

      Affiliations

    • Utah State Hospital, Provo, UT, USA
    • ,
  • Cassandra Burns

      Affiliations

    • Texas A and M University, College Station, TX, USA

References 

  1. Verzijl HT, van den Helm B, Veldman B, Hamel BC, Kuyt LP, Padberg GW, et al. A second gene for autosomal dominant Mobius syndrome is localized to chromosome 10q, in a Dutch family. Am Hum Genet. 1999;65:752–756
  2. Zuker RM, Manktelow RT. A smile for the Mobius’ syndrome patient. Ann Plast Surg. 1989;22:188–194
  3. Cohen SR, Thompson JW. Variants of Mobius’ syndrome and central neurologic impairment (Lindeman procedure in children). Ann Otol Rhinol Laryngol. 1987;96:93–100
  4. Gilmore RL, Falace P, Kanga J, Baumann R. Sleep-disordered breathing in Mobius syndrome. J Child Neurol. 1991;6:73–77
  5. Nardelli E, Vio M, Ghersini L, Rizzuto N. Mobius-like syndrome due to multiple cerebral abnormalities including hypoplasia of the descending tracts. A case report. J Neurol. 1982;227:11–19
  6. Miller MT, Stromland K. The Mobius sequence (a relook). J AAPOS. 1999;3:199–208
  7. Kahane JC. Pathophysiological effects of Mobius syndrome on speech and hearing. Arch Otolaryngol. 1979;105:29–34
  8. Kawai M, Momoi T, Fujii T, Nakano S, Itagaki Y, Mikawa H. The syndrome of Mobius sequence, peripheral neuropathy, and hypogonadotrophic hypogonadism. Am J Med Genetic. 1990;37:578–582
  9. Kremer H, Kuyt LP, van dem Helm B, van Reen M, Leunissin JA, Hamel BC, et al.  Localization of a gene for Mobius syndrome to chromosome 3q by linkage analysis in a Dutch family. Hum Mol Genet. 1996;5:1367–1371
  10. Johansson M, Wentz E, Fernell E, Stromland K, Miller MT, Gillberg C. Autistic disorders in Mobius sequence (a comprehensive study of 25 individuals). Dev Med Child Neurol. 2001;43:338–345
  11. Gillberg C, Steffenberg S. Autistic behavior in Mobius syndrome. Acta Paediatr Scand. 1989;78:314–316
  12. Gillberg C, Winndergard I. Childhood psychosis in a case of Moebius syndrome. Neuropediatrics. 1984;15:147–149
  13. Giannini AJ, Tamulonis D, Giannini MC, Loiselle RH, Spirtos G. Defective response to social cues in Mobius’ syndrome. J Nerv Ment Dis. 1984;173:174–175
  14. Graf WD, Shepard TH. Uterine contraction in the development of Mobius syndrome. J Child Neurol. 1997;12:225–227
  15. Kumar D. Moebius syndrome. J Med Genet. 1990;27:122–126
  16. Leong S, Ashwell KW. Is there a zone of vascular vulnerability in the fetal brain stem?. Neurotoxicol Teratol. 1997;19:265–275
  17. Donahue SP, Wenger SL, Steele MW, Gorin MB. Broad spectrum Mobius syndrome associated with a 1; 11 chromosome translocation. Ophthalmic Paediatr Genet. 1993;14:17–21
  18. Slee JJ, Smart RD, Viljoen DL. Deletion of chromosome 13 in Moebius syndrome. J Med Genet. 1991;28:413–414
  19. Ziter FA, Wiser WC, Robinson A. Three generation pedigree of a Mobius syndrome variant with chromosome translocation. Arch Neurol. 1977;34:437–442
  20. Nishikawa M, Ichiyama T, Hayashi T, Furukawa S. Mobius-like syndrome associated with a 1;2 chromosome translocation. Clin Genet. 1997;51:122–123
  21. Critchley HD, Simmon A, Daly EM, Russell A, van Amelsvoort Teck, Robertson DM, et al.  Prefrontal and medial temporal correlates of repetitive violence to self and others. Biol Psychiatry. 2000;47:928–934
  22. Horowitz AV, Widom CS, McLaughlin J, White HR. The impact of childhood abuse and neglect on adult mental health (a prospective study). J Health Soc Behav. 2001;42:184–201
  23. Raine A, Lencz T, Bihrle S, LaCasse L, Colletti P. Reduced prefrontal gray matter volume and reduced autonomic activity in antisocial personality disorder. Arch Gen Psychiatry. 2000;57:119–127
  24. Flint J. Behavioral phenotypes (conceptual and methodological issues). Am J Med Genet. 1998;81:235–240
  25. Brunner HG, Nelen M, Breakefield XO, Ropers HH, Van Ost BA. Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Science. 1993;262:578–580
  26. Nelson RJ, Demas GE, Huang PL, Fishman MC, Dawson VL, Dawson TM, et al.  Behavioral abnormalities in male mice lacking neuronal nitric oxide synthase. Nature. 1995;378:383–386
  27. Anderson LT, Ernst M. Self-injury in Lesch-Nyhan disease. J Autism Dev Disord. 1994;24:67–81
  28. Puranam RS, Eubanks JH, Heinemann SF, McNamara JO. Chromosomal localization of gene for human glutamate receptor subunit-7. Somat Cell Mol Genet. 1993;28:581–588
  29. Sparkes RS, Lan N, Klisak I, Mohandas T, Diep A, Kojis T, et al.  Assignment of a serotonin 5HT-2 receptor gene (5HTR2) to human chromosome 13q14-21 and mouse chromosome 14. Genomics. 1991;9:461–465

PII: S0010-440X(03)00144-5

doi: 10.1016/S0010-440X(03)00144-5

Comprehensive Psychiatry
Volume 44, Issue 6 , Pages 462-465 , November 2003

Article Tools