Comprehensive Psychiatry
Volume 44, Issue 4 , Pages 293-302, July 2003

Prevalence of human immunodeficiency virus, hepatitis b, and hepatitis c among homeless persons with co-occurring severe mental illness and substance use disorders

  • W.Dean Klinkenberg

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Dean Klinkenberg, Ph.D., Missouri Institute of Mental Health, 5400 Arsenal St, St Louis, MO 63139, USA
    • Missouri Institute of Mental Health, University of Missouri School of Medicine, St Louis, MO, USA
  • ,
  • Robert J Caslyn

      Affiliations

    • Gerontology Program, University of Missouri-St Louis, MO, USA
  • ,
  • Gary A Morse

      Affiliations

    • Community Alternatives, St Louis, MO, St Louis, MO, USA
  • ,
  • Robert D Yonker

      Affiliations

    • Department of Psychology, University of Missouri-St Louis, USA
  • ,
  • Suzanne McCudden

      Affiliations

    • Missouri Institute of Mental Health, University of Missouri School of Medicine, St Louis, MO, USA
  • ,
  • Fassil Ketema

      Affiliations

    • Department of Pathology, University of Maryland, Baltimore, MD, USA
  • ,
  • Niel T Constantine

      Affiliations

    • Department of Pathology, University of Maryland, Baltimore, MD, USA

Abstract 

This study was undertaken to determine the prevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) among homeless persons with co-occurring severe mental illness (SMI) and substance use disorders and to determine associated risk factors. As part of a longitudinal study of the effectiveness of integrated treatment for homeless persons with SMI and substance abuse or dependence, serological testing was performed to ascertain the prevalence of HIV, HBV, and HCV. At baseline, 6.2% of participants (11/172) were HIV-positive. Nearly one third of participants (37/114) had evidence of prior exposure to HBV, and 30% (34/114) were antibody positive for HCV. About 44% of participants (50/114) had a reactive test for either HBV or HCV. Having a reactive test was strongly associated with substance use, especially with a history of injection drug use. A significant threat exists to the health and well-being of homeless person with SMI due to high prevalence of blood-borne pathogens. Mental health providers need to play a proactive role in the identification of health-related needs and to assist with access to general health services for persons with SMI.

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 Supported by Grant No. R18 MH-51391 from the National Institute of Mental Health.

PII: S0010-440X(03)00094-4

doi:10.1016/S0010-440X(03)00094-4

Comprehensive Psychiatry
Volume 44, Issue 4 , Pages 293-302, July 2003