Comprehensive Psychiatry
Volume 44, Issue 3 , Pages 213-219 , May 2003

Interactive computer-training as a therapeutic tool in Alzheimer’s disease

  • Marc Hofmann

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Marc Hofmann, M.D., Division of Psychiatry Research, University of Zürich, Lenggstrasse 31, CH-8029 Zürich 8, Switzerland
    • Department of Psychiatry, University Basle, Basle, Switzerland
  • ,
  • Alexander Rösler

      Affiliations

    • Department of Neurology, University Frankfurt, Frankfurt, Germany
  • ,
  • Wolfram Schwarz

      Affiliations

    • Department of Psychiatry, University Basle, Basle, Switzerland
  • ,
  • Franz Müller-Spahn

      Affiliations

    • Department of Psychiatry, University Basle, Basle, Switzerland
  • ,
  • Kurt Kräuchi

      Affiliations

    • Department of Psychiatry, University Basle, Basle, Switzerland
    • Department of Neurology, University Frankfurt, Frankfurt, Germany
    • Division of Psychiatric Research, University of Zürich, Zürich, Switzerland
  • ,
  • Christoph Hock

      Affiliations

    • Division of Psychiatric Research, University of Zürich, Zürich, Switzerland
  • ,
  • Erich Seifritz

      Affiliations

    • Division of Psychiatric Research, University of Zürich, Zürich, Switzerland

References 

  1. Taulbee LR, Folsom JC. Reality orientation for geriatric patients. J Hosp Commun Psychiatry. 1966;17:133–135
  2. Ermini-Fünfschilling D, Meier D. Memory training (an important part of a “Milieu Therapy” for patients with senile dementia. Gedächtnis-training: Wichtiger Bestandteil der Milieutherapie bei seniler Demenz). Z Gerontol Geriatr. 1995;28:190–195
  3. Romero B, Eder G. Self-Maintenance therapy (concept of a neuropsycho-logical therapy in Alzheimer’s disease). Z Gerontopsychol Psychiatr. 1992;5:267–282
  4. Landauer TK, Bjork RA. Optimal rehearsal patterns and name learning. In:  Grundberg M,  Morris P,  Sykes R editor. Practical Aspects of Memory. London, UK: Academic Press; 1978;
  5. Bäckmann L. Memory training and memory improvement in Alzheimer’s disease (rules and exceptions). Acta Neurol Scand. 1992;139:84–89
  6. Gianutsos R. The computer in cognitive rehabilitation (it’s not just a tool anymore). J Head Trauma Rehabil. 1992;7:26–35
  7. Christiansen C, Abreu B, Ottenbacher K, Huffman K, Masel B, Culpepper R. Task performance in virtual environments used for cognitive rehabilitation after traumatic brain injury. Arch Phys Med Rehabil. 1998;79:888–892
  8. Brooks BM, McNeil JE, Rose FD, Greenwood RJ, Attree EA, Leadbetter AG. Route learning in a case of amnesia (preliminary investigation into the efficacy of training in a virtual environment). Neuropsychol Rehabil. 1999;9:63–76
  9. Schreiber M, Schweizer A, Lutz K, Kalveram KT, Jaencke L. Potential of an interactive computer-based training in the rehabilitation of dementia (an initial study). Neuropsychol Rehabil. 1999;9:155–167
  10. Hofmann M, Hock C, Müller-Spahn F. Computer-based cognitive training in Alzheimer′s disease patients. Ann NY Acad Sci. 1996;777:249–254
  11. Hofmann M, Hock C, Kühler A, Müller-Spahn F. Interactive computer-based cognitive training in patients with Alzheimer’s disease. J Psychiatry Res. 1996;30:493–501
  12. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. Ed. 3. Rev.. Washington, DC: American Psychiatric Association; 1987;
  13. McKhann G, Drachmann D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer’s disease (report of the NINCDS-ADRDA work group under auspices of the Department of Health and Human Service Task Force in Alzheimer’s Disease). Neurology. 1984;34:939–944
  14. Huges CP, Berg L, Danzinger WL, Coben LA, Martin RL. A new clinical scale for the staging of dementia. Br J Psychiatry. 1982;140:566–572
  15. Folstein MF, Folstein SE, McHugh PR. Mini-mental State. A practical method for grading the cognitive state of patients for the clinician. J Psychiatry Res. 1975;12:189–198
  16. Raitan RM. Trail Making Test. Manual for Administration, Scoring and Interpretation. Indianapolis, IN: Indiana University Press; 1956;
  17. Oswald WD, Fleischmann UM. Nünberger-Alters-Inventar (NAI) 3, überarbeitete und ergänzte Auflage, NAI-Testmaterial und Textband. Göttingen, Germany: Hogrefe Verlag für Psychologie; 1995;
  18. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry. 1979;134:382–389
  19. Eslinger PJ, Damasio AR. Preserved motor learning in Alzheimer’s disease (implications for anatomy and behavior). J Neurosci. 1986;6:3006–3009
  20. Gabrieli JDG. Cognitive neuroscience of human memory. Ann Rev Psychol. 1998;49:87–115
  21. Lezak MD. Depression. In: Muriel , Deutsch , Lezak  editor. Neuropsychological Assessment. Ed. 3. New York, NY: Oxford University Press; 1995;p. 325–327 499–522
  22. Ilsley JE, Moffoot APR, O’Carroll RE. An analysis of memory dysfunction in major depression. J Affect Disord. 1995;35:1–9
  23. Mohs RC, Ashman TA, Jantzen K, Albert M, Brandt J, Gordon B. A study of the efficacy of a comprehensive memory enhancement program in healthy elderly persons. Psychiatry Res. 1998;27:77:183–195
  24. Jay GM, Willis SL. Influence of direct computer experience on older adults’ attitudes toward computers. J Gerontol. 1992;47:250–257
  25. Suslow T, Arolt V. Effectiveness of computer-assisted attention training of schizophrenic patients. Psychiatr Prax. 1998;25:105–110

 E.S. is supported by grants from the Swiss National Science Foundation, SNF no. 63-58040.99.

PII: S0010-440X(03)00006-3

doi: 10.1016/S0010-440X(03)00006-3

Comprehensive Psychiatry
Volume 44, Issue 3 , Pages 213-219 , May 2003